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Antigenic Specificity | KHDC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KHDC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KHDC1 antibody is human, mouse and rat reactive. At least three isoforms of KHDC1 are known to exist; this antibody will only detect the longest isoform. KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4). |
Immunogen | Anti-KHDC1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid peptide near the N-terminus of human KHDC1. |
Other Names | KHDC1 Antibody, NDG1, C6orf148, bA257K9.4, KH homology domain-containing protein 1 |
Gene, Accession # | KHDC1, Gene ID: 80759, NCBI: NP_085045, UniProt: Q4VXA5 |
Catalog # | 600-401-CE2 |
Price | $475 |
Order / More Info | KHDC1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |