Vinculin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Vinculin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Vinculin antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Vinculin antibody is human, mouse and rat reactive. At least three isoforms of Vinculin are known to exist. Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5). |
| Immunogen | Anti-Vinculin antibody was prepared from whole rabbit serum produced by repeated immunizations with a 23 amino acid peptide near the internal region of human Vinculin. |
| Other Names | Vinculin Antibody, MV, MVCL, CMD1W, CMH15, HEL114, Vinculin, Metavinculin, MV |
| Gene, Accession # | VCL, Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
| Catalog # | 600-401-FW4 |
| Price | $475 |
| Order / More Info | Vinculin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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