Glial Fibrillary Acidic Protein (GFAP) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Glial Fibrillary Acidic Protein (GFAP) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | serum |
| Size | 100 µL |
| Concentration | Sufficient for 10 mini blots (total final volume 100 ml at 1:1000 dilution) |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-GFAP antibody was prepared from monospecifc neat serum. The antibody is directed against bovine glial fibrillary acidic proteins. Expect reactivity with the following species based on sequence homology: human, mouse, rat. Cross reactivity with GFAP from other species has not been determined. Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers. Therefore, GFAP antibody is ideal for investigators involved in neuropathologic diseases and more generally in Neuroscience. |
| Immunogen | Anti-GFAP Antibody was produced in rabbit by repeated immunizations with recombinant and purified bovine glial fibrillary acidic protein. |
| Other Names | gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, cb345. |
| Gene, Accession # | GFAP, Gene ID: 281189, UniProt: Q28115 |
| Catalog # | 100-401-D60 |
| Price | $475 |
| Order / More Info | Glial Fibrillary Acidic Protein (GFAP) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 27147665 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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