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Antigenic Specificity | ZEB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZEB1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZEB1 from other sources has not been determined. ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in post gastrulation embryogenesis. ZEB1 binds to the promoter of several hemopoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy. |
Immunogen | Anti-ZEB1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the internal region of human ZEB1. |
Other Names | ZEB1 Antibody, BZP, TCF8, AREB6, FECD6, NIL2A, PPCD3, ZFHEP, ZFHX1A, DELTAEF1, Zinc finger E-box-binding homeobox 1, NIL-2-A zinc finger protein, TCF-8 |
Gene, Accession # | ZEB1, Gene ID: 6935, NCBI: NP_001121600.1, UniProt: P37275 |
Catalog # | 600-401-GD0 |
Price | $475 |
Order / More Info | ZEB1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |