Mucin Gastric Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityMucin Gastric
Clone45M1
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, rabbit
IsotypeIgG1
FormatProtein A purified
Size100 µg
Concentration1.0 mg/ml
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionAnti-Mucin Gastric antibody was purified from mouse ascites by protein A chromatography. This product reacts with human, mouse, rat, and rabbit. Cross reactivity with Mucin Gastric from other sources has not been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. This antibody is suitable for researchers interested in neuroscience research, developmental signaling, and cell adhesion.
ImmunogenMucin Gastric antibody was produced in mice by repeated immunizations with mucin from human ovarian cyst fluid.
Other NamesMG1, MUC5, MUC9, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Sublingual gland mucin
Gene, Accession #MUC5B, Gene ID: 727897, NCBI: NP_002449.2, UniProt: Q9HC84
Catalog #200-301-P41
Price$485
Order / More InfoMucin Gastric Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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