Edit |   |
Antigenic Specificity | Mucin Gastric |
Clone | 45M1 |
Host Species | Mouse |
Reactive Species | human, mouse, rat, rabbit |
Isotype | IgG1 |
Format | Protein A purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Mucin Gastric antibody was purified from mouse ascites by protein A chromatography. This product reacts with human, mouse, rat, and rabbit. Cross reactivity with Mucin Gastric from other sources has not been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. This antibody is suitable for researchers interested in neuroscience research, developmental signaling, and cell adhesion. |
Immunogen | Mucin Gastric antibody was produced in mice by repeated immunizations with mucin from human ovarian cyst fluid. |
Other Names | MG1, MUC5, MUC9, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Sublingual gland mucin |
Gene, Accession # | MUC5B, Gene ID: 727897, NCBI: NP_002449.2, UniProt: Q9HC84 |
Catalog # | 200-301-P41 |
Price | $485 |
Order / More Info | Mucin Gastric Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |