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Antigenic Specificity | ErpD/Arp37 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Borrelia burgdorferi |
Isotype | n/a |
Format | Protein A purified |
Size | 25 µL |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. It is directed against, and shows specific reactivity for, Borrelia burgdorferi ErpD protein. Reactivity with ErpD/Arp37 protein from other sources has not been determined. This product is antibody made against Erp (ospE/F-Related Protein), also known as Arp37, from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. Erp proteins from Borrelia burgdorferi are postulated to be lipoproteins, based on their predicted amino acid sequences. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Several studies have demonstrated that infected humans and animals produce antibodies directed against Erp proteins within the first 2-4 weeks of infection, indicative of Erp synthesis during the initial stages of vertebrate infection. It is postulated that surface-exposed Erp proteins could facilitate interactions with host tissues during the establishment of vertebrate infection. |
Immunogen | MBP-fusion protein corresponding to Borrelia burgdorferi ErpD/Arp37 protein. |
Other Names | Rabbit anti-ErpD Antibody, rabbit anti-Arp37 Antibody, rabbit anti-Arp37/ErpD Antibody, Arp37, Borrelia burgdorferi ErpD |
Gene, Accession # | BB_F01, Gene ID: 1194073, NCBI: NP_045437.1, UniProt: G5IXI1 |
Catalog # | 200-401-C09S |
Price | $125 |
Order / More Info | ErpD/Arp37 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | PubMed: 32187539 |