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Antigenic Specificity | SYNPO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SYNPO Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SYNPO from other sources has not been determined. SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity. |
Immunogen | Anti-SYNPO antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human SYNPO. |
Other Names | SYNPO Antibody, KIAA1029, Synaptopodin |
Gene, Accession # | SYNPO NCBI: NP_001103444.1, UniProt: Q8N3V7 |
Catalog # | 600-401-EY3 |
Price | $475 |
Order / More Info | SYNPO Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |