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Antigenic Specificity | IL-22 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IL-22 Receptor antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. IL-22 antibody is human, mouse, and rat reactive. Multiple isoforms of IL-22 are known to exist. Interleukin-22 (IL-22) is a cytokine important for the modulation of tissue responses during inflammation (1). Unlike the distantly related IL-10, IL-22 does not inhibit the production of proinflammatory cytokines in monocytes in response to LPS, but it has some inhibitory effects on IL-4 production from Th2 T cells. IL-22 is expressed by both the adaptive arm of the immune system such as CD4 T cell subsets including Th17 cells, as well as by innate lymphocytes such as NK and LTi-like cells (2). IL-22 is highly expressed in several chronic inflammatory conditions, and studies suggest that IL-22 plays both inflammatory and protective roles (3). |
Immunogen | Anti-IL-22 receptor antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the internal region of human IL-22 |
Other Names | IL-22 Antibody, TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23, ZCYTO18, UNQ3099/PRO10096, Interleukin-22, Cytokine Zcyto18 |
Gene, Accession # | IL22, Gene ID: 50616, NCBI: NP_065386, UniProt: Q9GZX6 |
Catalog # | 600-401-BV7 |
Price | $475 |
Order / More Info | IL-22 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |