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Antigenic Specificity | GABA Transporter 1 (GAT1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-GABA Transporter 1 antibody is directed against rat GABA Transporter 1. GABA Transporter 1 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse. Gamma-aminobutyric acid (GABA) Antibody detects GABA which is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia. GAT-1 is thought to play a key role in epileptogenesis. Anti-GAT1 Antibody is ideal for investigators involved in Neuroscience. |
Immunogen | Anti-GABA Transporter 1 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. |
Other Names | Sodium- and chloride-dependent GABA transporter 1, Solute carrier family 6 member 1, GAT-1, Slc6a1, Gabt1, Gat1 |
Gene, Accession # | Slc6a1, Gene ID: 79212, UniProt: P23978 |
Catalog # | 612-401-D56 |
Price | $475 |
Order / More Info | GABA Transporter 1 (GAT1) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |