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Antigenic Specificity | ZIP12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZIP12 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least four isoforms of ZIP12 are known to exist. ZIP12 antibody is predicted to not cross-react with other ZIP family members. The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease. |
Immunogen | Anti-ZIP12 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human ZIP12. |
Other Names | ZIP12 Antibody, ZIP-12, LZT-Hs8, bA570F3.1, ZIP12, Zinc transporter ZIP12, LIV-1 subfamily of ZIP zinc transporter 8 |
Gene, Accession # | SLC39A12, Gene ID: 221074, NCBI: NP_001138667.1, UniProt: Q504Y0 |
Catalog # | 600-401-GE4 |
Price | $475 |
Order / More Info | ZIP12 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |