NMDA NR1 Subunit Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | NMDA NR1 Subunit |
| Clone | R1JHL |
| Host Species | Mouse |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | supernatant |
| Size | 15 µg |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-NMDA NR1 Subunit antibody is directed against rat NMDA NR1 subunit protein. The antibody was clarified from tissue culture supernatant. Reactivity is expected in rat and mouse. Cross reactivity with NMDA NR1 receptor from other species has not been determined. NMDA NR1 Subunit antibody detects NMDA NR1 receptor protein. The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1-subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. NMDA NR1 Subunit antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research. |
| Immunogen | Anti-NMDA NR1 Subunit Antibody was produced by repeated immunizations with a fusion proteins containing amino acids 1-564 of the rat NR1 subunit of the NMDA receptor. |
| Other Names | mouse anti-NMDA NR1 Antibody, Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1, NMD-R1, Grin1 |
| Gene, Accession # | Grin1, Gene ID: 24408, NCBI: NP_058706.1, UniProt: P35439 |
| Catalog # | 900-301-C85 |
| Price | $475 |
| Order / More Info | NMDA NR1 Subunit Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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