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Antigenic Specificity | Piccolo |
Clone | 6H9-B6 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2b kappa |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Piccolo Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Piccolo from human, mouse, rat based on 100% homology with the immunizing sequence. No cross-reactivity to Bassoon. Cross-reactivity with Piccolo from other sources has not been determined. Neuroscience research. Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains. In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones). Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1. |
Immunogen | Piccolo Antibody was produced in mice by repeated immunizations raised against a full length protein. |
Other Names | ACZ Antibody, Aczonin Antibody, PCLO Antibody, Pico Antibody, presynaptic cytomatrix protein Antibody, protein piccolo, Brain-derived HLMN protein, Multidomain presynaptic cytomatrix protein |
Gene, Accession # | PCLO, Gene ID: 27445, NCBI: NP_055325.2, UniProt: Q9Y6V0 |
Catalog # | 200-301-G30 |
Price | $485 |
Order / More Info | Piccolo Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |