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Antigenic Specificity | ZBED3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZBED3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2. Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. |
Immunogen | Anti-ZBED3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the N-terminus of human ZBED3. |
Other Names | ZBED3 Antibody, Zinc finger BED domain-containing protein 3, Axin-interacting protein |
Gene, Accession # | ZBED3, Gene ID: 84327, NCBI: NP_001316493.1, UniProt: Q96IU2 |
Catalog # | 600-401-GB1 |
Price | $475 |
Order / More Info | ZBED3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |