BECLIN1 phospho S234 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityBECLIN1 phospho S234
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified, no preservative
Size100 µL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionAnti-Beclin1 pS234 Antibody is directed against Beclin 1 protein phosphorylated at S234. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated beclin1. Minimal reactivity occurs against non-phosphorylated beclin1. Reactivity against Beclin 1 occurs from human sources. However, reactivity is also expected against bovine, canine, mouse, non-human primate, rat, and sheep. Beclin-1 plays a key role in tumor suppression and autophagy. It has been suggested that autophagy proteins such as beclin-1 can inhibit tumorigenesis and that decreased expression of these proteins may contribute to the development of human malignancies. Beclin-1 has been shown to interact with 14-3-3 proteins through Akt-mediated phosphorylation at Ser234. Beclin 1 pS234 Antibody is ideal for researchers interested in cancer research.
ImmunogenAnti-Phospho-Ser234 Beclin-1 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 of human Beclin-1 conjugated to KLH.
Other NamesRun domain Beclin-1 interacting and cysteine-rich containing protein, Rubicon, Beclin-1 associated RUN domain containing protein
Gene, Accession #BECN1, Gene ID: 8678, NCBI: NP_001300927.1, UniProt: Q14457
Catalog #600-401-W96
Price$475
Order / More InfoBECLIN1 phospho S234 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific ReferencesPubMed: 28253954
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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