Synapsin I phospho S549 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificitySynapsin I phospho S549
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunoaffinity purified
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry, Western Blot
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DescriptionAnti-Synapsin I pS549 antibody is directed against rat Synapsin I. Synapsin I pS549 was affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling of the synapsin I band is blocked by lambda-phosphatase treatment. Reactivity is expected from the following species based on 100% sequence homology: bovine, canine, human, mouse, and non-human primate. Synapsin I pS549 antibody is directed against rat Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Ser 549 along with Ser 62 and Ser 67 are the sites of synapsin I that are phosphorylated by MAP kinase. Phosphorylation and subsequent dephosphorylation of this site is thought to play a key role in synaptic vesicle trafficking. Anti-Synapsin I pS549 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
ImmunogenAnti-Synapsin I pS549 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser549 of Synapsin I.
Other NamesSynapsin I, SYN1, Synapsin-1
Gene, Accession #Syn1, Gene ID: 24949, NCBI: NP_001104252.1, UniProt: P09951
Catalog #612-401-C94
Price$475
Order / More InfoSynapsin I phospho S549 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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