Edit |   |
---|---|
Antigenic Specificity | CCDC134 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CCDC134 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CCDC134 from other sources has not been determined. The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines. |
Immunogen | Anti-CCDC134 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human CCDC134. |
Other Names | CCDC134 Antibody, dJ821D11.3, Coiled-coil domain-containing protein 134 |
Gene, Accession # | CCDC134, Gene ID: 79879, NCBI: NP_079097, UniProt: Q9H6E4 |
Catalog # | 600-401-AF1 |
Price | $475 |
Order / More Info | CCDC134 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |