Rhodopsin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Rhodopsin |
| Clone | 1D4 |
| Host Species | Mouse |
| Reactive Species | amphibians, mammalian |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 100 µL |
| Concentration | Titrated value sufficient to run approximately 10 mini blots. |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Rhodopsin antibody is directed against bovine Rhodopsin. Rhodopsin antibodies are Protein G purified from cell culture supernantant. Reactivity is predicted to human and mouse based on strong homology. Cross reactivity from other sources has not been determined. Rhodopsin antibody detects rhodopsin which is a photoreceptor protein found in retinal rods. It is a complex formed by the binding of retinaldehyde, the oxidized form of retinol, to the protein opsin and undergoes a series of complex reactions in response to visible light resulting in the transmission of nerve impulses to the brain. Mutation of the rhodopsin gene is a major contributor to various retinopathies such as retinitis pigmentosa. The disease-causing protein generally aggregates with ubiquitin in inclusion bodies, disrupts the intermediate filament network and impairs the ability of the cell to degrade non-functioning proteins which leads to photoreceptor apoptosis. Other mutations on rhodopsin lead to X-linked congenital stationary night blindness, mainly due to constitutive activation, when the mutations occur around the chromophore binding pocket of rhodopsin. Several other pathological states relating to rhodopsin have been discovered including poor post-Golgi trafficking, dysregulative activation, rod outer segment instability and arrestin binding. Anti-Rhodopsin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. |
| Immunogen | Anti-Rhodopsin Monoclonal Antibody was produced in mouse by repeated immunizations with purified native bovine rhodopsin. |
| Other Names | OPN2, Rhodopsin, RHO, Anti-Rhodopsin monoclonal, photoreceptor proteins |
| Gene, Accession # | RHO, Gene ID: 509933, UniProt: P02699 |
| Catalog # | 200-301-E29 |
| Price | $485 |
| Order / More Info | Rhodopsin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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