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Antigenic Specificity | Setd1a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | neat |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Setd1a Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Setd1a from other species not tested. SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. Anti-Setd1a Antibody is ideal for research in Epigenetics and Gene Expression. |
Immunogen | Anti-Setd1a Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Setd1a: two containing an amino acid sequence from the N-terminal region of the protein and one containing an amino acid sequence from the internal region of the protein. |
Other Names | Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1 |
Gene, Accession # | Setd1a, Gene ID: 9739, NCBI: NP_055527.1, UniProt: E9PYH6 |
Catalog # | 100-401-V94 |
Price | $445 |
Order / More Info | Setd1a Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |