AKT Isoform Antibody Sampler Kit Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-AKT Isoform Antibody Sampler Kit antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | AKT Isoform Antibody Sampler Kit |
| Clone | various |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 1 Kit |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This primary antibody kit has been carefully chosen to recognize all 3 isoforms of AKT. Anti-AKT1 antibody is directed against human AKT1. Anti-AKT2 antibody is directed against human AKT2. Anti-AKT3 antibody is directed against human AKT3. The antibodies detect both unphosphorylated and phosphorylated forms of the protein. The antibodies were purified from ascites by Protein A chromatography. This primary antibody kit is designed to detect and quantify endogenous protein levels of human AKT1, AKT2 and AKT3. Each antibody is designed to recognize a specific isoform of AKT. AKT is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation. Anti-AKT Antibodies are ideal for investigators involved in Cell Signaling, Neuroscience and Signal Transduction research. |
| Immunogen | All Anti-AKT isoform specific Antibodies were produced by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT1, AKT2 or AKT3 protein. |
| Other Names | AKT isoform antibody kit, AKT-1, AKT-2, AKT-3, Protein kinase Akt antibody, Protein kinase B antibody, RAC-gamma serine/threonine-protein kinase, RAC-PK-gamma, antibody sampler, |
| Gene, Accession # | AKT1, AKT2, AKT3 UniProt: P31749 |
| Catalog # | K401 |
| Price | $349 |
| Order / More Info | AKT Isoform Antibody Sampler Kit Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.