LDL-R Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-LDL-R antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | LDL-R |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-LDL-R Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with LDL-R from other sources has not been determined. The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in the LDL-R gene cause the autosomal dominant disorder, familial hypercholesterolemia. Along with SCARB1, CLDN1, and the tetraspanin superfamily member CD81, LDL-R has been reported to be an entry factor for the Hepatitis C virus. At least three isoforms of LDL-R are known to exist. |
| Immunogen | Anti-LDL-R antibody was prepared from chicken egg fractions produced by repeated immunizations with an 18 amino acid synthetic peptide near the internal region of human LDL-R. |
| Other Names | LDL-R Antibody, FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor |
| Gene, Accession # | LDLR, Gene ID: 3949, NCBI: NP_000518, UniProt: P01130 |
| Catalog # | 200-901-CJ1 |
| Price | $475 |
| Order / More Info | LDL-R Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies