Edit |   |
---|---|
Antigenic Specificity | YPEL3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-YPEL3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with YPEL3 from other sources has not been determined. YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors. |
Immunogen | Anti-YPEL3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human YPEL3. |
Other Names | YPEL3 Antibody, Protein yippee-like 3 |
Gene, Accession # | YPEL3, Gene ID: 83719, NCBI: NP_001138996.1, UniProt: P61236 |
Catalog # | 600-401-GA5 |
Price | $475 |
Order / More Info | YPEL3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |