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Antigenic Specificity | IL-15RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IL-15RA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Multiple isoforms of IL-15RA are known to exist. Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2. |
Immunogen | Anti- IL-15RA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the internal region of human IL-15RA. |
Other Names | IL-15RA Antibody, CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha |
Gene, Accession # | IL15RA, Gene ID: 3601, NCBI: NP_001243694, UniProt: Q13261 |
Catalog # | 600-401-BU4 |
Price | $475 |
Order / More Info | IL-15RA Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |