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Antigenic Specificity | Cyclin L1/L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 500 µg |
Concentration | 5.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The product was purified from monospecific antiserum by Protein A chromatography. This antibody will react with all forms of Cyclin L b (cyclin L1b and cyclin L2b). Cross reactivity with Cyclin L beta proteins from other sources is unknown. Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase. |
Immunogen | This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic construct consisting of full length Human Cyclin L1b protein. |
Other Names | rabbit anti-Cyclin L1/L2 Antibody, rabbit anti-Cyclin L1 Antibody, rabbit anti-Cyclin L2 Antibody, Cyclin L beta, CCNL1, CCNL2, Paneth cell-enhanced expression protein |
Gene, Accession # | CCNL1, CCNL2, Gene ID: 57018, NCBI: NP_064703.1, UniProt: Q9UK58 |
Catalog # | 200-401-890 |
Price | $525 |
Order / More Info | Cyclin L1/L2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |