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Antigenic Specificity | JMJD6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-JMJD6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with JMJD6 from other sources has not been determined. The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing. |
Immunogen | Anti-JMJD6 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the N-terminus of human JMJD6. |
Other Names | JMJD6 Antibody, PSR, PTDSR, PTDSR1, KIAA0585, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Histone arginine demethylase JMJD6, Protein PTDSR |
Gene, Accession # | JMJD6, Gene ID: 23210, NCBI: Q6NYC1, UniProt: Q6NYC1 |
Catalog # | 600-401-CC1 |
Price | $475 |
Order / More Info | JMJD6 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |