TCRbeta Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TCRbeta |
| Clone | H57-597 |
| Host Species | Hamster Armenian |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µg |
| Concentration | 0.5mg/mL |
| Applications | Flow Cytometry, IF Microscopy, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated TCRbeta Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse TCRbeta. Cross reactivity with TCRbeta from other sources has not been tested. Anti-TCRbeta is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR. |
| Immunogen | Anti-TCRbeta Antibody (Monoclonal) was produced by repeated immunizations with TCRbeta antigen. |
| Other Names | Tib, TCRbeta, T cell receptor beta chain, Tcrb |
| Gene, Accession # | Tcrb, Gene ID: 21577 |
| Catalog # | 200-B02-N92 |
| Price | $365 |
| Order / More Info | TCRbeta Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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