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Antigenic Specificity | ZIMP10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZIMP10 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms are known to exist; this antibody will recognize all three. ZIMP10 antibody is predicted to not cross-react with other PIAS protein family members. ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development. |
Immunogen | Anti-ZIMP10 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide near the N-terminus of human ZIMP10. |
Other Names | ZIMP10 Antibody, MIZ, RAI17, ZIMP10, hZIMP10, TRAFIP10, KIAA1224, Zinc finger MIZ domain-containing protein 1, PIAS-like protein Zimp10 |
Gene, Accession # | ZMIZ1, Gene ID: 57178, NCBI: NP_065071.1, UniProt: Q9ULJ6 |
Catalog # | 600-401-GD8 |
Price | $475 |
Order / More Info | ZIMP10 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |