Adenosine Deaminase Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityAdenosine Deaminase
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, bovine calf spleen
Isotypen/a
Formatserum
Size2 mL
Concentration90 mg/mL
ApplicationsELISA, Immunoprecipitation, Western Blot
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DescriptionThis product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-rabbit serum, purified and partially purified Adenosine Deaminase [Calf Spleen]. Cross reactivity against Adenosine Deaminase from other tissues and species may occur but have not been specifically determined. Adenosine Deaminase catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. It plays an important role in purine metabolism and in adenosine homeostasis. Adenosine Deaminase modulates signaling by extracellular adenosine, therefore contributes indirectly to cellular signaling events. It acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. Adenosine Deaminase enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. It enhances CD4+ T-cell differentiation and proliferation. And acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change. It stimulates plasminogen activation. It also plays a role in male fertility and a protective role in early post implantation embryonic development.
ImmunogenAdenosine Deaminase [Calf Spleen]
Other Namesrabbit anti-Adenosine Deaminase Antibody, Adenosine deaminase, Adenosine aminohydrolase
Gene, Accession #ADA, Gene ID: 280712, NCBI: NP_776312.1, UniProt: P56658
Catalog #100-401-140
Price$1225
Order / More InfoAdenosine Deaminase Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

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