CREB-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CREB-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | serum |
| Size | 100 µL |
| Concentration | 2.56 mg/ml |
| Applications | ELISA, Gel Shift, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-CREB-1 was prepared from monospecific antiserum by delipidation and immunoadsorption against an E.coli lysate immobilized on agarose beads. Anti-CREB-1 (p43) may react non-specifically with other proteins. A partial cross-reactivity is observed against CREM-1 protein. Anti CREB-1 Antibody recognizes CREB (cAMP response element-binding), a cellular transcription factor. CREB binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the downstream genes. CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, the neurotrophin BDNF (Brain-derived neurotrophic factor), tyrosine hydroxylase, and many neuropeptides (such as somatostatin, enkephalin, VGF, and corticotropin-releasing hormone). CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB proteins are expressed in many animals, including humans. CREB has a well-documented role in neuronal plasticity and long-term memory formation in the brain. |
| Immunogen | CREB-1 (p43) peptide corresponding to a region near the N-terminus of the human protein, conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Other Names | rabbit anti-CREB1 Antibody, rabbit anti-p43 antibody, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1, CREB-1, CREB1, p43 |
| Gene, Accession # | CREB1, Gene ID: 1385, NCBI: CAG28545.1, UniProt: P16220 |
| Catalog # | 100-401-195 |
| Price | $475 |
| Order / More Info | CREB-1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 11571785 // 21757760 // 22050776 // 24487386 // 24739710 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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