EZH2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityEZH2
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size50 µg
Concentration1 mg/ml
ApplicationsChip
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DescriptionAnti-EZH2 Antibody was purified by Protein G chromatography. Cross-reactivity with EZH2 from other species has not been determined. EZH2 is a histone-lysine methyltransferase which methylates `Lys-9' and `Lys-27' of histone H3, leading to transcriptional repression. It is a member of the polycomb group (PcG) family which form multimeric protein complexes and are involved in maintaining the transcriptional repressive state of genes over successive cell generations. The EZH2 activity is dependent on the association with other components of the PRC2 complex (EED, SUZ12/JJAZ1, RBBP4 and RBBP7). EZH2 may play a role in the hematopoietic and internal nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer. Anti-EZH2 Antibody is ideal for research in Epigenetics, Gene Expression, Neuroscience and Cancer.
ImmunogenAnti-EZH2 Antibody was produced in mice by repeated immunizations containing an amino acid sequence from the internal region of the human EZH2 protein.
Other NamesHistone-lysine N-methyltransferase EZH2, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, KMT6
Gene, Accession #EZH2, Gene ID: 2146, NCBI: NP_001190176.1, UniProt: Q15910
Catalog #200-301-W46
Price$485
Order / More InfoEZH2 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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