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Antigenic Specificity | EZH2 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 50 µg |
Concentration | 1 mg/ml |
Applications | Chip |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-EZH2 Antibody was purified by Protein G chromatography. Cross-reactivity with EZH2 from other species has not been determined. EZH2 is a histone-lysine methyltransferase which methylates `Lys-9' and `Lys-27' of histone H3, leading to transcriptional repression. It is a member of the polycomb group (PcG) family which form multimeric protein complexes and are involved in maintaining the transcriptional repressive state of genes over successive cell generations. The EZH2 activity is dependent on the association with other components of the PRC2 complex (EED, SUZ12/JJAZ1, RBBP4 and RBBP7). EZH2 may play a role in the hematopoietic and internal nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer. Anti-EZH2 Antibody is ideal for research in Epigenetics, Gene Expression, Neuroscience and Cancer. |
Immunogen | Anti-EZH2 Antibody was produced in mice by repeated immunizations containing an amino acid sequence from the internal region of the human EZH2 protein. |
Other Names | Histone-lysine N-methyltransferase EZH2, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, KMT6 |
Gene, Accession # | EZH2, Gene ID: 2146, NCBI: NP_001190176.1, UniProt: Q15910 |
Catalog # | 200-301-W46 |
Price | $485 |
Order / More Info | EZH2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |