STAT6 phospho Y641 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Search, find, compare suppliers for anti-STAT6 phospho Y641 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | STAT6 phospho Y641 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 25 µL |
| Concentration | 1.13 mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This affinity purified antibody is directed against human STAT6 pY641 protein. The product was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with STAT6 pY641 protein from human at 100% based on homology with the immunizing sequence. Reactivity against homologues from other sources is not known. STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT6 is involved in interleukin-4 signaling. It interacts with NCOA1 via its C-terminal LXXLL motif. Further it induces the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Following stimulation by IL-4 and IL-3, Stat6 is activated via phosphorylation at Tyr641 and translocates to the nucleus where it regulates cytokine-induced gene expression. |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a phosphorylated synthetic peptide corresponding to residues surrounding Tyrosine Y641 of human STAT6 protein. |
| Other Names | rabbit anti-STAT6 pY641 antibody, phosphorylated STAT6 antibody, STAT-6, STAT 6, Signal transducer and activator of transcription 6 antibody, IL-4 Stat, Interleukin-4 Stat |
| Gene, Accession # | STAT6, Gene ID: 6778, NCBI: NP_001171549.1, UniProt: P42226 |
| Catalog # | 600-401-C67S |
| Price | $125 |
| Order / More Info | STAT6 phospho Y641 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.
Return to Antibodies