Histone H2A.Zac pan Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityHistone H2A.Zac pan
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size50 µg
Concentration0.7 mg/ml
ApplicationsELISA, Chip, IF Microscopy, Western Blot
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DescriptionAnti-Histone H2A.Zac pan Antibody was purified by affinity purification. Cross reactivity with other species was not tested. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatinstructure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ``histone code''. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of the histone H2A variant H2A.Z is associated with the promoters of active genes. Anti-Histone H2A.Zac is ideal for research in Gene Expression, Chromatin Remodeling and Epigenetics.
ImmunogenAnti-Histone H2A.Zac Antibody was produced in rabbits by repeated immunizations with a synthetic peptide from histone H2A.Z acetylated at lysines 5, 7 and 11.
Other NamesHistone H2A.Z, H2A/z
Gene, Accession #H2AFZ, Gene ID: 3015, NCBI: NP_002097, UniProt: P0C0S5
Catalog #600-401-X49
Price$475
Order / More InfoHistone H2A.Zac pan Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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