Langerin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Langerin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Langerin Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Langerin from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Langerin from other sources has not been determined. Anti-Langerin Antibody detects mouse Langerin. Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin (CD207) recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin (CD207) is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin (CD207) is thus a potent inducer of membrane superimposition and zippering leading to BG formation. Anti-Langerin Antibody is ideal for investigators involved in Toll Like Receptors, signaling, and extracellular matrix research. |
| Immunogen | Langerin Antibody was produced from whole rabbit serum prepared by repeated immunizations with mouse Langerin protein at an internal amino acid sequence. |
| Other Names | Clec4k, C-type lectin domain family 4 member K, Langerin, CD207 |
| Gene, Accession # | Cd207, Gene ID: 246278, NCBI: NP_659192.2, UniProt: Q8VBX4 |
| Catalog # | 200-401-H89 |
| Price | $525 |
| Order / More Info | Langerin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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