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Antigenic Specificity | TPT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TPT1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TPT1 from other sources has not been determined. TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome. |
Immunogen | Anti-TPT1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid peptide near the internal region of human TPT1. |
Other Names | TPT1 Antibody, HRF, p02, p23, TCTP, Translationally-controlled tumor protein, Fortilin |
Gene, Accession # | TPT1, Gene ID: 7178, NCBI: NP_001273202.1, UniProt: P13693 |
Catalog # | 600-401-FM4 |
Price | $475 |
Order / More Info | TPT1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |