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Antigenic Specificity | ZC3H12B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ZC3H12B Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ZC3H12B from other sources has not been determined. ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS). |
Immunogen | Anti-ZC3H12B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the N-terminus of human ZC3H12B. |
Other Names | ZC3H12B Antibody, MCPIP2, CXorf32, MCPIP2, Probable ribonuclease ZC3H12B, MCP-induced protein 2 |
Gene, Accession # | ZC3H12B, Gene ID: 340554, NCBI: NP_001010888.3, UniProt: Q5HYM0 |
Catalog # | 600-401-GC5 |
Price | $475 |
Order / More Info | ZC3H12B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |