TIP47 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTIP47
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry, Western Blot
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DescriptionAnti-TIP47 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TIP47 from other sources has not been determined. Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.
ImmunogenAnti-TIP47 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the N-terminus of human TIP47.
Other NamesTIP47 Antibody, PP17, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, Perilipin-3, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Placental protein 17, PLIN3, M6PRBP1
Gene, Accession #PLIN3, Gene ID: 26762, NCBI: NP_036338, UniProt: Q96D42
Catalog #600-401-FF2
Price$475
Order / More InfoTIP47 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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