Peripherin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Peripherin |
| Clone | 7C5 |
| Host Species | Mouse |
| Reactive Species | mouse, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 100 µL |
| Concentration | n/a |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Peripherin antibody is directed against rat Peripherin. The antibody is protein G purified from concentrated clarified cell culture supernate. Reactivity is expected from most mammalian. Cross reactivity with Peripherin from other species is not known. Peripherin Antibody detects Peripherin. Peripherin is a ~57kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. Anti-Peripherin Antibody is ideal for investigators involved in Neuroscience and Cancer research. |
| Immunogen | Anti-Peripherin Antibody (Monoclonal) was produced by repeated immunizations with recombinant rat peripherin expressed in E. coli. |
| Other Names | NEF4, PRPH1, Peripherin, prph, prph1 antibody, PNS antibodies, monoclonal anti-peripherin, mouse monoclonal antibody to peripherin, monoclonal anti-peripherin antibody produced in mouse |
| Gene, Accession # | Prph, Gene ID: 3414, UniProt: P21807 |
| Catalog # | 900-301-E11 |
| Price | $475 |
| Order / More Info | Peripherin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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