Paxillin Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityPaxillin
ClonePXC-10
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, chicken
IsotypeIgG1
FormatProtein A purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Western Blot
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DescriptionAnti-Paxillin antibody was purified from mouse ascites by protein A chromatography. This product reacts with human, mouse, rat, and chicken. Cross reactivity with Paxillin from other sources has not been determined. The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. This antibody is suitable for researchers interested in growth factors and signal transduction.
ImmunogenPaxillin antibody was produced in mice by repeated immunizations with recombinant protein corresponding to the C-terminal part of chicken paxillin (amino acids 305-559).
Other NamesPaxillin antibody, PXN
Gene, Accession #PXN, Gene ID: 5829, NCBI: NP_001074324.1, UniProt: P49023
Catalog #200-301-P44
Price$485
Order / More InfoPaxillin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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