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Antigenic Specificity | LSD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 50 µg |
Concentration | 2.0 mg/ml |
Applications | Chip, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LSD1 Antibody was purified by Protein G chromatography. Cross reactivity with other species was not tested. LSD1 (lysine specific demethylase 1) is a component of the histone demethylase complex that uses FAD as a prosthetic group. LSD1 may have a dual effect on gene transcription. As it demethylates the mono- and dimethylated `Lys-4' of histone H3, which are associated with transcriptional activation, LSD1 can act as a repressor of gene expression. However, LSD1 is also capable of demethylating `Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to activation of androgen receptor target genes. LSD1 therefore is ideal for research in different processes such as Stem and Cancer Cell Biology, Embryonic Development, Epigenetics and Cell Differentiation and Proliferation. |
Immunogen | Anti-LSD1 Antibody was produced in rabbits by repeated immunizations with a full length recombinant protein of human LSD1. |
Other Names | Lysine-specific histone demethylase 1A, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, AOF2, KDM1 |
Gene, Accession # | KDM1A, Gene ID: 23028, NCBI: NP_001009999.1, UniProt: O60341 |
Catalog # | 200-401-W52 |
Price | $475 |
Order / More Info | LSD1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |