LSD1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityLSD1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size50 µg
Concentration2.0 mg/ml
ApplicationsChip, Western Blot
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DescriptionAnti-LSD1 Antibody was purified by Protein G chromatography. Cross reactivity with other species was not tested. LSD1 (lysine specific demethylase 1) is a component of the histone demethylase complex that uses FAD as a prosthetic group. LSD1 may have a dual effect on gene transcription. As it demethylates the mono- and dimethylated `Lys-4' of histone H3, which are associated with transcriptional activation, LSD1 can act as a repressor of gene expression. However, LSD1 is also capable of demethylating `Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to activation of androgen receptor target genes. LSD1 therefore is ideal for research in different processes such as Stem and Cancer Cell Biology, Embryonic Development, Epigenetics and Cell Differentiation and Proliferation.
ImmunogenAnti-LSD1 Antibody was produced in rabbits by repeated immunizations with a full length recombinant protein of human LSD1.
Other NamesLysine-specific histone demethylase 1A, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, AOF2, KDM1
Gene, Accession #KDM1A, Gene ID: 23028, NCBI: NP_001009999.1, UniProt: O60341
Catalog #200-401-W52
Price$475
Order / More InfoLSD1 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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