Edit |   |
---|---|
Antigenic Specificity | TESPA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TESPA1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TESPA1 antibody is human specific. At least three isoforms TESPA1 are known to exist. TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development (1). TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species (2). TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage (3). TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus (1,4). |
Immunogen | Anti-TESPA1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the N-terminus of human TESPA1. |
Other Names | TESPA1 Antibody, HSPC257, KIAA0748, HSPC257, Protein TESPA1, Thymocyte-expressed positive selection-associated protein 1 |
Gene, Accession # | TESPA1, Gene ID: 9840, NCBI: NP_001092285.1, UniProt: A2RU30 |
Catalog # | 600-401-FC7 |
Price | $475 |
Order / More Info | TESPA1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |