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Antigenic Specificity | SIRT5 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-SIRT5 Antibody is an IgY fraction that has been affinity purified by immunoaffinity purification. Cross reactivity with SIRT5 from other sources has not been determined. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle. |
Immunogen | Anti-SIRT5 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human SIRT5. |
Other Names | SIRT5 Antibody, SIR2L5, SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5 |
Gene, Accession # | SIRT5, Gene ID: 23408, NCBI: NP_036373, UniProt: Q9NXA8 |
Catalog # | 200-901-EM0 |
Price | $475 |
Order / More Info | SIRT5 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |