Vinculin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Vinculin |
| Clone | 7E10 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, chicken, rabbit |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Vinculin antibody is purified via Protein A purification. Vinculin antibody is human, mouse, rat, rabbit and chicken reactive. At least three isoforms of Vinculin are known to exist. Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5). |
| Immunogen | Anti-Vinculin antibody was prepared from whole mouse serum produced by repeated immunizations with a 23 amino acid peptide near the N-terminus of human Vinculin. |
| Other Names | CMD1W, CMH15, Metavinculin, MVCL |
| Gene, Accession # | VCL, Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
| Catalog # | 200-301-FW6 |
| Price | $485 |
| Order / More Info | Vinculin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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