KDEL Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | KDEL |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 200 µg |
| Concentration | 1 mg/mL |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-KDEL Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with KDEL from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Recognizes KDEL proteins, GRP94, Grp78, PDI and calreticulin. It may also see ERp57 and ERp29. Cross-reactivity with KDEL from other sources has not been determined. Organell Marker research. The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. |
| Immunogen | KDEL Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against KDEL containing synthetic peptide immunogen. |
| Other Names | Lys Asp Glu Leu, K-D-E-L, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention, Kdelr1 |
| Gene, Accession # | KDELR1, Gene ID: 10945, NCBI: NP_006792.1, UniProt: P24390 |
| Catalog # | 600-401-F85 |
| Price | $445 |
| Order / More Info | KDEL Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.