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Antigenic Specificity | BIM |
Clone | 1C2C8 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Bim Monoclonal Antibody was immunoaffinity chromatography purified IgG. Cross reactivity with Bim [1C2C8] from other sources has not been determined. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines. |
Immunogen | Anti-Mouse monoclonal Bim antibody produced by repeated immunizations in mice with a recombinant protein corresponding to amino acids 2 to 198 of human Bim. |
Other Names | Bim Antibody, BAM, BIM, BOD, BCL2L11 |
Gene, Accession # | BCL2L11, Gene ID: 10018, NCBI: NP_619527, UniProt: O43521 |
Catalog # | 200-301-Z71 |
Price | $485 |
Order / More Info | BIM Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |