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Antigenic Specificity | CD27 |
Clone | O323 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | fluorescein (FITC) conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fluorescein conjugated CD27 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD27. Reactivity is observed against human CD27, Baboon, Cynomolgus, Rhesus, and Squirrel Monkey. Cross reactivity with CD27 from other sources has not been tested. Anti-CD27 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-kB and SAPK/JNK activation. |
Immunogen | Anti-CD27 Antibody (Monoclonal) was produced by repeated immunizations with CD27 antigen. |
Other Names | CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, TNFRSF7 |
Gene, Accession # | CD27, Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842 |
Catalog # | 200-302-N65 |
Price | $399 |
Order / More Info | CD27 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |