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Antigenic Specificity | BTLA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-BTLA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. BTLA antibody is human specific. At least two isoforms of BTLA are known to exist. The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain. Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells. Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis. |
Immunogen | Anti-BTLA antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the internal region of human BTLA. |
Other Names | BTLA Antibody , BTLA1, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein |
Gene, Accession # | BTLA, Gene ID: 151888, NCBI: NP_861445, UniProt: Q7Z6A9 |
Catalog # | 600-401-Z97 |
Price | $475 |
Order / More Info | BTLA Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |