IRF7 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityIRF7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsImmunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-IRF7 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with IRF7 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with IRF7 from other sources has not been determined. IRF7 antibody detects the human IRF7. Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. Anti-IRF7 antibodies are ideal for investigators involved in transcription factors, infectious disease and cytokines and growth factors research.
ImmunogenIRF7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to the c-terminus of human IRF7.
Other NamesInterferon regulatory factor 7
Gene, Accession #IRF7, Gene ID: 3665, NCBI: NP_001563.2, UniProt: Q92985
Catalog #600-401-H00
Price$475
Order / More InfoIRF7 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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