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Antigenic Specificity | IRF7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IRF7 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with IRF7 with Human, Rat and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with IRF7 from other sources has not been determined. IRF7 antibody detects the human IRF7. Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. Anti-IRF7 antibodies are ideal for investigators involved in transcription factors, infectious disease and cytokines and growth factors research. |
Immunogen | IRF7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to the c-terminus of human IRF7. |
Other Names | Interferon regulatory factor 7 |
Gene, Accession # | IRF7, Gene ID: 3665, NCBI: NP_001563.2, UniProt: Q92985 |
Catalog # | 600-401-H00 |
Price | $475 |
Order / More Info | IRF7 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |