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Antigenic Specificity | KPNA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KPNA3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with KPNA3 from other sources has not been determined. Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is similar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia. |
Immunogen | Anti-KPNA3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the carboxy end of human KPNA3. |
Other Names | KPNA3 Antibody, SRP1, SRP4, IPOA4, hSRP1, SRP1gamma, QIP2, Importin subunit alpha-4, Importin alpha Q2, Qip2 |
Gene, Accession # | KPNA3, Gene ID: 3839, NCBI: NP_002258, UniProt: O00505 |
Catalog # | 600-401-CG1 |
Price | $475 |
Order / More Info | KPNA3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |