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Antigenic Specificity | TRIM28 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TRIM28 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least three isoforms of TRIM28 are known to exist; this antibody will detect all three isoforms. TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation. |
Immunogen | Anti-TRIM28 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human TRIM28. |
Other Names | TRIM28 Antibody, KAP1, TF1B, RNF96, TIF1B, KAP1, Transcription intermediary factor 1-beta, E3 SUMO-protein ligase TRIM28, TIF1-beta |
Gene, Accession # | TRIM28, Gene ID: 10155, NCBI: NP_005753.1, UniProt: Q13263 |
Catalog # | 600-401-FP2 |
Price | $475 |
Order / More Info | TRIM28 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |