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Antigenic Specificity | Recombinant DIG (DIG45) |
Clone | DIG45 |
Host Species | Recombinant |
Reactive Species | Digitalis sp. |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-DIG (VHH) Antibody is a recombinant antibody. The clone was isolated from a library prepared from a hyper-immunized llama host and purified by affinity chromatography from bacterial culture. Expect reactivity against DIG-labeled probes and proteins. Digoxigenin is a cardenolide steroid isolated from the plant species of the genus Digitalis. It has a role as a hapten and a plant metabolite and can be obtained by hydrolysis of digoxin. Digoxigenin or DIG is one of the most common reporters used with nucleotides and requires the use of a conjugated anti-digoxigenin antibody. Since digoxigenin is a plant-related chemical not found in mammalian tissues, it is widely used as a method for generating non-radioactive probes, and is an alternative to biotin. DIG is an all-purpose immuno-tag, and in particular a standard marker for immunohistochemistry and in situ hybridization that supports both chromogenic and chemiluminescence detection.A single-domain antibody (sdAb) is a small antibody fragment consisting of the monomeric variable domain derived from camelid heavy chain-only immunoglobulins naturally found in llamas, alpacas and camels. Also known as VHH antibodies, these are the smallest functional antigen-binding fragment that occurs in nature (12 - 14 kDa) and are now being used in biotechnology as a novel antibody scaffold. The small size of the VHH single domain antibody makes it very attractive for use in diagnostic imaging and potentially therapeutic applications. |
Immunogen | n/a |
Other Names | anti-Digoxigenin, Digoxigenin (DIG), 1672-46-4, Lanadigenin, Digoxigenine, UNII-NQ1SX9LNAU, DIG, CHEBI:42098, HSDB 7108, NQ1SX9LNAU, EINECS 216-806-2, BRN 0096479, 4-(3,12,14-Trihydroxy-10,13-Dimethyl-Hexadecahydro-Cyclopenta[a]Phenanthren-17-Yl)-5h-Furan-2-One |
Gene, Accession # | Digoxigenin |
Catalog # | 400-001-MG2 |
Price | $475 |
Order / More Info | Recombinant DIG (DIG45) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |