TLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTLR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry
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DescriptionAnti-TLR4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TLR4 antibody is predicted to not cross-react with other TLR protein family members. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.
ImmunogenAnti-TLR4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human TLR4.
Other NamesTLR4 Antibody, TOLL, CD284, TLR-4, ARMD10, Toll-like receptor 4, hToll
Gene, Accession #TLR4, Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206
Catalog #600-401-FG0
Price$475
Order / More InfoTLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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