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Antigenic Specificity | TLR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TLR4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. TLR4 antibody is predicted to not cross-react with other TLR protein family members. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis. |
Immunogen | Anti-TLR4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of human TLR4. |
Other Names | TLR4 Antibody, TOLL, CD284, TLR-4, ARMD10, Toll-like receptor 4, hToll |
Gene, Accession # | TLR4, Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206 |
Catalog # | 600-401-FG0 |
Price | $475 |
Order / More Info | TLR4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |